2-Fluorophenylacetyl chloride

CAS: 451-81-0

Ref. 3D-FF97431

Product Information

• Name: 2-Fluorophenylacetyl chloride
• Synonyms: 2-(2'-Fluorophenyl)acetyl chloride, 2-Fluorobenzeneacetyl chloride, Acetyl chloride, (o-fluorophenyl)-, Benzeneacetyl chloride, 2-fluoro-, o-Fluorophenylacetyl chloride

Description

2-Fluorophenylacetyl chloride is a chlorinating agent that selectively adds fluorine to carbonyl groups. It is used in the synthesis of homochiral synthons and in the production of fluorinated pharmaceuticals. The stereochemical outcome depends on the enolate employed, with an enolate derived from a chiral ketone or alcohol typically giving rise to a single diastereomer. The stereoselective addition of 2-fluorophenylacetyl chloride to alkenes is accomplished using a catalytic system that employs cyclopentadiene as the catalyst.

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.58 g/mol
• Formula: C₈H₆ClFO
• Purity: Min. 95%
• InChI: InChI=1S/C8H6ClFO/c9-8(11)5-6-3-1-2-4-7(6)10/h1-4H,5H2
• InChI key: InChIKey=KUMKNGTWQNSAQW-UHFFFAOYSA-N
• SMILES: O=C(Cl)Cc1ccccc1F