[(4S,5R)-4-Fluoro-5-(6-Methylaminopurin-9-Yl)Oxolan-2-Yl]Methanol

CAS: 126502-17-8

Ref. 3D-FF97806

Product Information

• Name: [(4S,5R)-4-Fluoro-5-(6-Methylaminopurin-9-Yl)Oxolan-2-Yl]Methanol
• Synonyms: 9-(2,3-Dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-N-methyl-9H-purin-6-amine, Fmadda, Nsc 625374, 9H-Purin-6-amine, 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-N-methyl-, 9-[(4xi)-2,3-dideoxy-2-fluoro-alpha-L-glycero-pentofuranosyl]-N-methyl-9H-purin-6-amine

Description

[(4S,5R)-4-Fluoro-5-(6-Methylaminopurin-9-yl)Oxolan-2-yl]methanol is a prodrug with pharmacokinetic properties that can be used to study the metabolism of azides. It is metabolized by deamination and amines to form alicyclic metabolites. [(4S,5R)-4-Fluoro-5-(6-Methylaminopurin-9-yl)Oxolan-2-yl]methanol has been shown to have pharmacokinetic properties similar to those of the parent drug, azide. This drug has been shown to have potential for use as a chemotherapeutic agent in vitro studies using cultured cells and cycloaliphatic mediated studies.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.26 g/mol
• Formula: C₁₁H₁₄FN₅O₂
• Purity: Min. 95%
• InChI: InChI=1S/C11H14FN5O2/c1-13-9-8-10(15-4-14-9)17(5-16-8)11-7(12)2-6(3-18)19-11/h4-7,11,18H,2-3H2,1H3,(H,13,14,15)/t6-,7-,11+/m0/s1
• InChI key: InChIKey=BBUZAEMTTVCRAD-OKTBNZSVSA-N
• SMILES: CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)C[C@@H]1F