(2-Fluoro-4-formyl-5-hydroxy-6-methyl-pyridin-3-yl)methoxyphosphonic acid

CAS: 90932-80-2

Ref. 3D-FF99489

Product Information

• Name: (2-Fluoro-4-formyl-5-hydroxy-6-methyl-pyridin-3-yl)methoxyphosphonic acid

Description

At a pH of 7.4, the protonated form predominates and is the active form. In acidic environments, the fluorine atom is protonated and the molecule exists as a phosphite tautomer. At pH 3.0, the predominant form is a phosphorylase tautomer, which is inactive. The kinetic behavior of this compound can be described by equation 1:

(2-Fluoro-4-formyl-5-hydroxy-6-methyl-pyridin-3-yl)methoxyphosphonic acid + H+ → (2-Fluoro-4-(protonated)-5-(protonated or deprotonated)-6-(protonated or deprotonated)-methylpyridin-3-yl)methoxyphosphonic acid

The enzyme phosphohydrolase converts this compound to methylmalonyl phosphate and ATP by using one proton

• Brand: Biosynth

Chemical properties

• Molecular weight: 265.13 g/mol
• Formula: C₈H₉FNO₆P
• Purity: Min. 95%
• InChI: InChI=1S/C8H9FNO6P/c1-4-7(12)5(2-11)6(8(9)10-4)3-16-17(13,14)15/h2,12H,3H2,1H3,(H2,13,14,15)
• InChI key: InChIKey=UPISIGUJMYQUBS-UHFFFAOYSA-N
• SMILES: Cc1nc(F)c(COP(=O)(O)O)c(C=O)c1O