6-Oxo simvastatin
CAS: 130468-11-0
Ref. 3D-FFA46811
| 1mg | 194.00 € | ||
| 2mg | 309.00 € | ||
| 5mg | 436.00 € | ||
| 10mg | 646.00 € | ||
| 25mg | 1,159.00 € |
Product Information
6-Oxo simvastatin is a homolog of the cholesterol synthesis inhibitor simvastatin. It inhibits the enzyme HMG-CoA reductase, which is involved in the production of cholesterol. 6-Oxo simvastatin can be extracted from microbial cultures and has been shown to inhibit microbial transformation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) into mevalonic acid during growth. 6-Oxo simvastatin has been shown to have potent inhibitory effects on HMG CoA reductase in subspecies that are resistant to other inhibitors such as lovastatin and pravastatin.
Chemical properties
Technical inquiry about: 3D-FFA46811 6-Oxo simvastatin
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