H-Glu(Glu-OH)-OH

CAS: 1116-22-9

Ref. 3D-FG108030

Product Information

• Name: H-Glu(Glu-OH)-OH
• Synonyms: H-?-Glu-Glu-OH, (2S)-2-{[(4S)-4-ammonio-4-carboxylatobutanoyl]amino}pentanedioate, <span class="text-smallcaps">L</smallcap>-Glutamic acid, <smallcap>L</span>-γ-glutamyl-, <span class="text-smallcaps">L</smallcap>-Glutamic acid, N-<smallcap>L</span>-γ-glutamyl-, <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-glutamic acid, Gamma-Glutamylglutamic Acid, Glutamic acid, N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-, <smallcap>L</span>-, Glutamic acid, N-<span class="text-smallcaps">L</span>-γ-glutamyl-, H-Gamma-Glu-Glu-Oh, L-gamma-glutamyl-L-glutamic acid, N-gamma-L-Glutamyl-L-glutamic acid, gamma-Glutamylglutamate, γ-<span class="text-smallcaps">L</smallcap>-Glutamyl-<smallcap>L</span>-glutamic acid, γ-Glutamylglutamic acid
• CAS: 1116-22-9

Description

H-Glu(Glu-OH)-OH is a synthetic amino acid that is currently being investigated as a diagnostic agent for the detection of intracellular protein degradation by matrix metalloproteinase-9 (MMP-9). H-Glu(Glu-OH)-OH is taken up by cells in a concentration and time dependent manner, with an uptake rate of approximately 1.6 x 10^6 molecules per cell per hour. The uptake mechanism is not yet known, but has been hypothesized to be due to receptor binding. H-Glu(Glu-OH)-OH binds to cerebellar granule cells and alters mitochondrial metabolism, which may be related to its effects on the ubiquitin proteasome pathway. This compound also has diagnostic potential for atherosclerosis and glutamate transport disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 276.24 g/mol
• Formula: C₁₀H₁₆N₂O₇
• Purity: Min. 95%