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Glibornuride
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Glibornuride

CAS: 26944-48-9

Ref. 3D-FG43275

1mgDiscontinued
2mgDiscontinued
5mgDiscontinued
10mgDiscontinued
25mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
Glibornuride
Synonyms:
  • Benzenesulfonamide, N-[[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)amino]carbonyl]-4-methyl-, [1S-(endo,endo)]-
  • Benzenesulfonamide, N-[[[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methyl-
  • Gluboride
  • Glutril
  • N-[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)carbamoyl]-4-methylbenzenesulfonamide
  • N-[[[(1S,2S,3R,4R)-3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methylbenzenesulfonamide
  • Ro 6-4563
  • Ro 6-4563/8
  • Urea, 1-(2-hydroxy-3-bornyl)-3-(p-tolylsulfonyl)-, (1R,2R,3S,4S)-
  • endo, endo-1-[(1R)-(2-Hydroxy-3-bornyl)]-3-(p-tolylsulfonyl)urea
  • See more synonyms
  • endo,endo-1-(2-Hydroxy-3-bornyl)-3-(p-tolylsulfonyl)urea
Description:

Glibornuride is a drug that inhibits dipeptidyl peptidase-IV (DDP-IV), which is an enzyme that degrades GLP-1, a hormone that stimulates insulin secretion from the pancreas. It has been shown to have significant hypoglycemic effect in patients with type 2 diabetes mellitus and it can be used as an antidiabetic agent. Glibornuride also inhibits sodium-dependent glucose co-transporters and fat synthesis. The drug has been found to have potential for use in the treatment of liver diseases such as nonalcoholic fatty liver disease by inhibiting the activity of lipogenic enzymes and reducing levels of fatty acid. Glibornuride is metabolized by cytochrome P450 enzymes in the liver cells to form its active form, glibenclamide, which then binds to ATP-sensitive potassium channels on hepatocytes, thereby reducing the release of glucose into blood.
Glibornuride

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
366.48 g/mol
Formula:
C18H26N2O4S
Purity:
Min. 95%
MDL:
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Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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