2-Hydroxy-3-naphthoic acid methyl ester

CAS: 883-99-8

Ref. 3D-FH00779

Product Information

• Name: 2-Hydroxy-3-naphthoic acid methyl ester
• Synonyms: Methyl 3-Hydroxy-2-naphthoate, 2-Hydroxynaphthalene-3-carboxylic acid methyl ester, 2-Naphthalenecarboxylic acid, 3-hydroxy-, methyl ester, 2-Naphthoic acid, 3-hydroxy-, methyl ester, 3-(Methoxycarbonyl)-2-naphthol, 3-Carbomethoxy-2-naphthol, 3-Hydroxy-2-naphthalenecarboxylic acid methyl ester, 3-Hydroxy-2-naphthoic acid methyl ester, Methyl 2-hydroxy-3-naphthoate, Methyl 2-hydroxy-3-naphthoic acid, Methyl 2-hydroxynaphthalene-3-carboxylate, Methyl 3-Hydroxynaphthalene-2-Carboxylate, Methyl 3-hydroxy-2-naphthalenecarboxylate, NSC 25175

Description

2-Hydroxy-3-naphthoic acid methyl ester (2HNEM) is a molecule that has a carbonyl group. It has been shown to be effective against certain viruses, including herpes simplex virus type 1 and human immunodeficiency virus type 1, by inhibiting the replication of viral DNA. 2HNEM has also been shown to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus, by binding to the surface of bacterial cells and blocking the synthesis of proteins required for cell division. 2HNEM binds to metal ions and forms hydrogen bonds with amino groups in its microenvironment. This shielding effect prevents protonation, which is necessary for enzyme activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 202.21 g/mol
• Formula: C₁₂H₁₀O₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H10O3/c1-15-12(14)10-6-8-4-2-3-5-9(8)7-11(10)13/h2-7,13H,1H3
• InChI key: InChIKey=YVVBECLPRBAATK-UHFFFAOYSA-N
• SMILES: COC(=O)c1cc2ccccc2cc1O