7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

CAS: 14003-96-4

Ref. 3D-FH117553

Product Information

• Name: 7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde
• CAS: 14003-96-4

Description

7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde is an activated molecule that exhibits significant cytotoxicity to human liver cancer cells. It inhibits the mitochondrial membrane potential, leading to the release of cytochrome c and apoptosis induction. 7HMOCA has been shown to be a reactive molecule with benzimidazole derivative properties. This compound depletes cellular glutathione levels and increases intracellular reactive oxygen species (ROS) levels, which leads to DNA fragmentation, cell cycle arrest, and ultimately apoptosis induction when combined with other agents. The fluorescence properties of this molecule have enabled its detection in living cells without the need for additional reagents or labeling.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.18 g/mol
• Formula: C₁₁H₈O₄
• Purity: Min. 95 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
• InChI key: InChIKey=RTHHSXOVIJWFQP-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)oc2c(C=O)c(O)ccc12