Product Information
- 3-Hydroxytricyclo[3.3.1.13,7]decane-1-carboxylic
- 3-Hydroxy--1-Amantane Carboxylic Acid
- 3-Hydroxy-1-adamantanecarboxylic acid
- 3-Hydroxy-1-Adamantane Carboxylic Acid
- (5R,7R)-3-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate
- 3-Hydroxytricyclo[3.3.1.1~3,7~]Decane-1-Carboxylic Acid
8-Hydroxyadamantane-1-carboxylic acid (8HA) is a drug that is used in the treatment of HIV. It is a prodrug that is converted to active form by the liver and then excreted by the kidneys. 8HA has antiviral activity against HIV and other viruses. The optimal reaction conditions for this compound are pH 7, chloride concentration 1M, copper concentration 0.5M, and temperature 50°C. 8HA binds to the viral envelope glycoprotein gp120 as well as to host cells in order to inhibit viral replication and replication. This compound also inhibits the production of antibodies, which may be due to its ability to bind with antibody molecules through an ionic bond at a neutral pH.
Chemical properties
Technical inquiry about: 3D-FH11848 8-Hydroxyadamantane-1-carboxylic acid
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