4-Hydroxyquinoline-2-carboxylic acid
CAS: 13593-94-7
Ref. 3D-FH123362
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
4-Hydroxyquinoline-2-carboxylic acid
Synonyms:
- 2-quinolinecarboxylic acid
- 4-hydroxy-
- 4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid
Description:
4-Hydroxyquinoline-2-carboxylic acid (4HQCA) is a drug that is an antagonist at the α7 nicotinic acetylcholine receptor. It has been shown to have significant effects on glutamate, kynurenate, and kynurenic acid levels in the brain. 4HQCA binds to the α7 nicotinic acetylcholine receptor with high affinity and specificity. This binding prevents agonists from activating the receptor, which can lead to neuronal death. 4HQCA also inhibits tryptophan hydroxylase activity, which may be responsible for its anti-depressive effects.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
189.17 g/mol
Formula:
C10H7NO3
Purity:
Min. 95%
InChI:
InChI=1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
InChI key:
InChIKey=HCZHHEIFKROPDY-UHFFFAOYSA-N
SMILES:
O=C(O)c1cc(=O)c2ccccc2[nH]1
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