7-Hydroxy-2-methyl-3-phenyl-chromen-4-one

CAS: 2859-88-3

Ref. 3D-FH12892

Product Information

• Name: 7-Hydroxy-2-methyl-3-phenyl-chromen-4-one
• Synonyms: 4H-1-benzopyran-4-one, 7-hydroxy-2-methyl-3-phenyl-, 7-Hydroxy-2-methyl-3-phenyl-4H-1-benzopyran-4-one, 7-Hydroxy-2-methylisoflavone, Isoflavone, 7-hydroxy-2-methyl-, NSC 108340

Description

7-Hydroxy-2-methyl-3-phenylchromen-4-one is a synthetic flavonoid that has been shown to have hepatoprotective activity. 7-Hydroxy-2-methylchromen-4-one has been found to act as an antioxidant by inhibiting the oxidation of lipids and proteins, which in turn prevents lipid peroxidation and oxidative damage to DNA. 7HMC also inhibits the growth of cancer cells and is used in the treatment of malaria. It has antiinflammatory properties and may be useful for inflammatory bowel disease or asthma. 7HMC also has antimalarial activity, as it inhibits protein synthesis in Plasmodium falciparum, the parasite that causes malaria. The molecule is converted into 7HMC by reacting with methoxy groups with hydroxyl groups on the side chain. This reaction can be catalyzed by allanrobinson reagents such as 2-(1,2,3,4,-

• Brand: Biosynth

Chemical properties

• Molecular weight: 252.26 g/mol
• Formula: C₁₆H₁₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C16H12O3/c1-10-15(11-5-3-2-4-6-11)16(18)13-8-7-12(17)9-14(13)19-10/h2-9,17H,1H3
• InChI key: InChIKey=BBCDTCKKROIGAB-UHFFFAOYSA-N
• SMILES: Cc1oc2cc(O)ccc2c(=O)c1-c1ccccc1