5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione

CAS: 2784-27-2

Ref. 3D-FH131980

Product Information

• Name: 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione
• Synonyms: 2,4-imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-, (Hydroxyphenyl)phenylhydantoin, (p-Hydroxyphenyl)phenylhydantoin, 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-, 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl- (9CI), 4-Hydroxydiphenylhydantoin, 4-Hydroxyphenytoin, 5-(4-Hydroxyphenyl)-5-phenyl hydantoin, 5-(4-Hydroxyphenyl)-5-phenyl-2,4-imidazolidinedione, 5-(p-Hydroxyphenyl)-5-phenylhydantoin, 5-Phenyl-5-p-hydroxyphenylhydantoin, Ccris 7051, Hpph, Hydantoin, 5-(p-hydroxyphenyl)-5-phenyl-, Hydroxydiphenylhydantoin, Hydroxyphenytoin, Nsc 156081, dl-5-(p-Hydroxyphenyl)-5-phenylhydantoin, p-Hydroxydiphenylhydantoin, p-Hydroxyphenytoin, para-Hydroxyphenytoin

Description

5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione (PPI) is a potent inducer of the cytochrome P450 enzyme system. This drug is metabolized to phenytoin, which is used for the treatment of epileptic seizures. PPIs are also used to treat diabetic neuropathy and other conditions. PPIs are potent inducers of the cytochrome P450 enzyme system and can induce hepatic drug metabolism, leading to an increased risk for drug interactions. PPIs have been shown to be effective against hypersensitivity syndrome, human serum albumin, and monoclonal antibody preparations in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 268.27 g/mol
• Formula: C₁₅H₁₂N₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)
• InChI key: InChIKey=XEEDURHPFVXALT-UHFFFAOYSA-N
• SMILES: O=C1NC(=O)C(c2ccccc2)(c2ccc(O)cc2)N1