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2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride
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2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride

CAS: 62732-44-9

Ref. 3D-FH133264

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Estimated delivery in United States, on Thursday 16 Jan 2025

Product Information

Name:
2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride
Synonyms:
  • 1H-cyclopenta[b]quinolin-9-amine
  • 2,3,5,6,7,8-hexahydro-
  • hydrochloride
  • 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
  • 1H-Cyclopenta[b]quinolin-9-amine, 2,3,5,6,7,8-hexahydro-
  • 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylamine
  • 9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinoline
  • Ipidacrine
  • Neuromidine
Description:

2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride (HCPQ) is a potent and selective inhibitor of the enzyme DPP-IV. HCPQ has been shown to reduce symptoms of type 2 diabetes by lowering glucose levels in the blood. The drug also inhibits cholinergic neurotransmission and may be used for the treatment of Alzheimer's disease and diabetic neuropathy. HCPQ binds to the catalytic site of DPP-IV and prevents it from breaking down an important signaling molecule called incretin insulin. This leads to an increase in intracellular calcium levels which can activate proteins involved in energy metabolism. HCPQ also inhibits acetylcholinesterase activity which may lead to neuronal death in Alzheimer's disease patients.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
188.27 g/mol
Formula:
C12H16N2
Purity:
Min. 95%
InChI:
InChI=1S/C12H16N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-7H2,(H2,13,14)
InChI key:
InChIKey=YLUSMKAJIQOXPV-UHFFFAOYSA-N
SMILES:
Nc1c2c(nc3c1CCC3)CCCC2
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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