4-Hydrazinocarbonyl-benzene-sulfonamide

CAS: 35264-29-0

Ref. 3D-FH149943

Product Information

• Name: 4-Hydrazinocarbonyl-benzene-sulfonamide
• Synonyms: 4-(Hydrazinocarbonyl)benzenesulfonamide, Benzoic Acid, 4-(Aminosulfonyl)-, Hydrazide

Description

4-Hydrazinocarbonyl-benzene-sulfonamide is a potent inhibitor of nitrous oxide (NO) production. It is an efficient method for the treatment of pulmonary diseases, such as chronic obstructive pulmonary disease (COPD). 4-Hydrazinocarbonyl-benzene-sulfonamide inhibits NO production by inhibiting the enzyme Nitric Oxide Synthase 1 (NOS1), which catalyzes the conversion of L-arginine to citrulline and NO. This inhibition prevents the formation of nitric oxide, leading to a decrease in inflammation and improved lung function. 4-Hydrazinocarbonyl-benzene-sulfonamide binds to an allosteric site on NOS1 and inhibits its activity with low micromolar affinity. This drug also has inhibitory activities against cytosolic NOS2, but does not inhibit constitutive NOS3 or endot

• Brand: Biosynth

Chemical properties

• Molecular weight: 215.23 g/mol
• Formula: C₇H₉N₃O₃S
• Purity: Min. 95%
• InChI: InChI=1S/C7H9N3O3S/c8-10-7(11)5-1-3-6(4-2-5)14(9,12)13/h1-4H,8H2,(H,10,11)(H2,9,12,13)
• InChI key: InChIKey=JIDAHYHCQJXNTD-UHFFFAOYSA-N
• SMILES: NNC(=O)c1ccc(S(N)(=O)=O)cc1