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4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester
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4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester

CAS: 53135-24-3

Ref. 3D-FH165241

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Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester
Synonyms:
  • 4-Hydroxy-2-Methyl-Pyrimidine-5-Carboxylic Acid Ethyl Ester
Description:

4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester is a potent inhibitor of human telomerase. The enzyme telomerase is involved in the synthesis of telomeres, which are repetitive DNA sequences at the ends of chromosomes that protect the chromosomes from deterioration or from fusion with other chromosomes. Telomeres shorten during each cell division, and eventually become too short to protect the chromosome. This leads to chromosomal instability and cell death. 4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester inhibits human telomerase by binding to it and preventing telomere replication. This drug has been shown to inhibit tumor growth in mice when used in combination with chemotherapy drugs.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
182.18 g/mol
Formula:
C8H10N2O3
Purity:
Min. 95%
InChI:
InChI=1S/C8H10N2O3/c1-3-13-8(12)6-4-9-5(2)10-7(6)11/h4H,3H2,1-2H3,(H,9,10,11)
InChI key:
InChIKey=KTZQDIINDVWLES-UHFFFAOYSA-N
SMILES:
CCOC(=O)c1cnc(C)[nH]c1=O
MDL:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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