4-Hydroxycarbazeran

CAS: 96724-43-5

Ref. 3D-FH165283

Product Information

• Name: 4-Hydroxycarbazeran

Description

4-Hydroxycarbazeran is an enzyme probe that belongs to the class of hydralazine. It is metabolized by aldehyde oxidase and sulfation. The kinetics of 4-hydroxycarbazeran has been studied in human lung explants and incubations, with results showing that it is rapidly hydrolyzed by an aldehyde oxidase and sulfation. Carbazarin, a related compound, is also metabolized by this enzyme system. Triclosan has been shown to inhibit 4-hydroxycarbazeran metabolism in vitro. Zoniporide, another related compound, inhibits the activity of aldehyde oxidase and sulfation in vivo.

• Brand: Biosynth

Chemical properties

• Molecular weight: 376.41 g/mol
• Formula: C₁₈H₂₄N₄O₅
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C18H24N4O5/c1-4-19-18(24)27-11-5-7-22(8-6-11)16-12-9-14(25-2)15(26-3)10-13(12)17(23)21-20-16/h9-11H,4-8H2,1-3H3,(H,19,24)(H,21,23)
• InChI key: InChIKey=YIFOKLMSOFKZBP-UHFFFAOYSA-N
• SMILES: CCNC(=O)OC1CCN(c2n[nH]c(=O)c3cc(OC)c(OC)cc23)CC1