Product Information
2-Hydroxyatorvastatin is a statin that inhibits the enzyme HMG-CoA reductase, which is responsible for the conversion of 3-hydroxy-3-methylglutaryl (HMG) to mevalonic acid. The matrix effect may be potentiated by other drugs that are potent inducers of cytochrome P450 enzymes, such as phenobarbital, phenytoin, and rifampicin. 2-Hydroxyatorvastatin has a long elimination half life, which may lead to drug interactions with other drugs that have short elimination half lives. Pharmacokinetic properties of this drug include a concentration-time curve and an lc-ms/ms method for detection. This product also has the potential to cause adverse effects such as myopathy or hepatotoxicity.
2-Hydroxyatorvastatin is an analytical method for quantifying 2-hydroxylated atorvastatin metabolites in human
Chemical properties
Technical inquiry about: 3D-FH171760 2-Hydroxyatorvastatin
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