5-Hydroxy lornoxicam

CAS: 123252-96-0

Ref. 3D-FH24031

Product Information

• Name: 5-Hydroxy lornoxicam
• Synonyms: 6-Chloro-4-hydroxy-N-(5-hydroxy-2-pyridinyl)-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-Dioxide, 3-E)-1,2-Thiazine-3-Carboxamide,6-Chloro-4-Hydroxy-N-(5-Hydroxy-2-2H-Thieno(, Pyridinyl)-2-Methyl-,1,1-Dioxide, (3E)-6-chloro-3-{hydroxy[(5-hydroxypyridin-2-yl)amino]methylidene}-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide

Description

5-Hydroxy lornoxicam is a non-steroidal anti-inflammatory drug that inhibits the production of prostaglandins. It binds to the enzyme cyclooxygenase, which converts arachidonic acid to prostaglandin H2, thereby inhibiting pain and inflammation in animals. The 5-hydroxyl group on lornoxicam may make it more metabolically stable than other non-steroidal drugs. Lornoxicam has been shown to be effective in clinical trials against pain in humans and is metabolized mainly by glucuronidation and excreted in the urine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 387.82 g/mol
• Formula: C₁₃H₁₀ClN₃O₅S₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H10ClN3O5S2/c1-17-10(13(20)16-9-3-2-6(18)5-15-9)11(19)12-7(24(17,21)22)4-8(14)23-12/h2-5,18-19H,1H3,(H,15,16,20)
• InChI key: InChIKey=NQOMZUZLRFQVLR-UHFFFAOYSA-N
• SMILES: CN1C(C(=O)Nc2ccc(O)cn2)=C(O)c2sc(Cl)cc2S1(=O)=O