3-Hydroxy phenytoin

CAS: 30074-03-4

Ref. 3D-FH24087

Product Information

• Name: 3-Hydroxy phenytoin
• Synonyms: 5-(3-Hydroxyphenyl)-5-phenyl hydantoin5-(3-Hydroxyphenyl)-5-phenyl-2,4-imidazolidinedione5-(m-Hydroxyphenyl)-5-phenylhydantoin, 2,4-Imidazolidinedione, 5-(3-hydroxyphenyl)-5-phenyl-, 3-Hydroxyphenytoin, 4-(M-Hydroxyphenyl)-4-Phenylperhydroimidazole-2,5-Dione, 5-(3-Hydroxyphenyl)-5-Phenylimidazolidine-2,4-Dione, 5-(3-Hydroxyphenyl)-5-phenyl-2,4-imidazolidinedione, 5-(m-Hydroxyphenyl)-5-phenylhydantoin, Hydantoin, 5-(m-hydroxyphenyl)-5-phenyl-, m-Hydroxydiphenylhydantoin

Description

3-Hydroxy phenytoin is a prodrug that is hydrolyzed in the human body to phenytoin. It is used for its pharmacokinetic properties, which are different from those of phenytoin. 3-Hydroxy phenytoin has been shown to have a greater solubility and better absorption than the drug it metabolizes to, with a plasma concentration peak occurring in two hours. 3-Hydroxy phenytoin has been shown to be metabolized by cytochrome P450 (CYP) enzymes and is subject to interactions with drugs that inhibit or induce these enzymes. 3-Hydroxy phenytoin also forms an inactive complex with human liver proteins, which may account for its prolonged elimination half-life.

• Brand: Biosynth

Chemical properties

• Molecular weight: 268.27 g/mol
• Formula: C₁₅H₁₂N₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C15H12N2O3/c18-12-8-4-7-11(9-12)15(10-5-2-1-3-6-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)
• InChI key: InChIKey=FSPRLRPJSPWQNC-UHFFFAOYSA-N
• SMILES: O=C1NC(=O)C(c2ccccc2)(c2cccc(O)c2)N1