8-Hydroxy warfarin

CAS: 17834-04-7

Ref. 3D-FH24168

Product Information

• Name: 8-Hydroxy warfarin
• Synonyms: 4,8-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one3-(a-Acetonylbenzyl)-4,8-dihydroxycoumarin, 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one, 2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-, 3-(Alpha-Acetonylbenzyl)-4,8-Dihydrocoumarin, 3-(Α-Acetonylbenzyl)-4,8-Dihydrocoumarin, 3-(α-Acetonylbenzyl)-4,8-dihydrocoumarin, 4-8-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one, 4,8-Dihydroxy-3-(3-Oxo-1-Phenylbutyl)-2H-1-Benzopyran-2-One, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one, Coumarin, 3-(α-acetonylbenzyl)-4,8-dihydroxy-

Description

8-Hydroxy warfarin is a drug that belongs to the group of anticoagulants. It is a hydroxylated derivative of warfarin. Warfarin inhibits the synthesis of vitamin K-dependent clotting factors and the activation of vitamin K-dependent proteins, which are necessary for blood coagulation. 8-Hydroxy warfarin is a more potent inhibitor than warfarin and also has stereoselective properties. The rate of metabolism and elimination half-life of 8-hydroxy warfarin are increased in rats compared with humans, possibly due to differences in cytochrome P450 enzymes. The clinical relevance of these findings has not been determined yet.

• Brand: Biosynth

Chemical properties

• Molecular weight: 324.33 g/mol
• Formula: C₁₉H₁₆O₅
• Purity: Min. 95%
• Color/Form: White/Off-White Solid
• InChI: InChI=1S/C19H16O5/c1-11(20)10-14(12-6-3-2-4-7-12)16-17(22)13-8-5-9-15(21)18(13)24-19(16)23/h2-9,14,21-22H,10H2,1H3
• InChI key: InChIKey=BHBOXPNWDGYJNB-UHFFFAOYSA-N
• SMILES: CC(=O)CC(c1ccccc1)c1c(O)c2cccc(O)c2oc1=O