2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline

CAS: 77314-23-9

Ref. 3D-FH24305

Product Information

• Name: 2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline
• Synonyms: N-Hydroxy-3-methyl-3H-imidazo[4,5-f]quinolin-2-amine1,3-Dihydro-3-methyl-2H-imidazo[4,5-f]quinolin-2-one oximeN-OH-IQ

Description

2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline (2HAIQ) is a reactive compound that binds to DNA. It has been shown to be a potent inhibitor of the enzyme cytosolic protein kinase C, which plays an important role in regulating cellular metabolism. 2HAIQ also inhibits the activity of enzymes such as hydroxylases and polymerases. The binding of 2HAIQ to DNA is thought to inhibit transcription by preventing RNA polymerase from transcribing DNA. 2HAIQ may also inhibit replication by binding to the dinucleotide phosphate molecule, which is essential for DNA synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 214.22 g/mol
• Formula: C₁₁H₁₀N₄O
• Purity: Min. 95%
• InChI: InChI=1S/C11H10N4O/c1-15-9-5-4-8-7(3-2-6-12-8)10(9)13-11(15)14-16/h2-6,16H,1H3,(H,13,14)
• InChI key: InChIKey=QYFQSQCBYZOECM-UHFFFAOYSA-N
• SMILES: Cn1c(NO)nc2c3cccnc3ccc21