7-(2-Hydroxypropyl)guanine
CAS: 56247-84-8
Ref. 3D-FH24490
| 1g | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
7-(2-Hydroxypropyl)guanine
Synonyms:
- 2-Amino-1,7-dihydro-7-(2-hydroxypropyl)-6H-purin-6-oneN7-(2-Hydroxypropyl)guanine
- 2-Amino-1,7-dihydro-7-(2-hydroxypropyl)-6H-purin-6-one
- 2-Amino-7-(2-hydroxypropyl)-6,7-dihydro-1H-purin-6-one
- 6H-Purin-6-one, 2-amino-1,7-dihydro-7-(2-hydroxypropyl)-
- 7-(2-Hydroxypropyl)Guanine
- N<sup>7</sup>-(2-Hydroxypropyl)guanine
- N7-(2-Hydroxypropyl)guanine
Description:
7-(2-Hydroxypropyl)guanine (7-HPG) is a nucleoside analogue that is used for the treatment of liver cancer. It is an alkylating agent, which reacts with cellular DNA to form crosslinks and inhibits DNA synthesis. 7-HPG is given intravenously and targets liver cells, as well as other tissues such as the pancreas and lung. The short-term exposure of 7-HPG in animals has not been found to cause any carcinogenic effects. This drug also has a neutral pH, making it suitable for use in patients who have difficulty tolerating acidic drugs. The repair mechanism of 7-HPG may be due to the cell type specificity or short duration of exposure.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
209.21 g/mol
Formula:
C8H11N5O2
Purity:
Min. 95%
InChI:
InChI=1S/C8H11N5O2/c1-4(14)2-13-3-10-6-5(13)7(15)12-8(9)11-6/h3-4,14H,2H2,1H3,(H3,9,11,12,15)
InChI key:
InChIKey=JVWVMKYNORDKGP-UHFFFAOYSA-N
SMILES:
CC(O)Cn1cnc2nc(N)[nH]c(=O)c21
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