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5-Hydroxyquinoline
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5-Hydroxyquinoline

CAS: 578-67-6

Ref. 3D-FH24498

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Estimated delivery in United States, on Tuesday 20 Aug 2024

Product Information

Name:
5-Hydroxyquinoline
Synonyms:
  • 5-Quinolinol5-HydroxyquinolineNSC 405729
  • NSC 405729
  • Quinolin-5-Ol
  • Timtec-Bb Sbb004118
  • quinolin-5(1H)-one
Description:

5-Hydroxyquinoline (5HQ) is a heterocyclic aromatic compound that has been used as a reagent for the synthesis of quinoline derivatives. It is synthesized by the reaction of 2,4-dichloro-1,3-quinolinediol with dimethylformamide and trifluoroacetic acid. The mechanism of this reaction is the nucleophilic attack of the hydroxy group on the C6 position of 5HQ. This reaction can be carried out in two steps: first, the hydroxy group attacks at the C6 position to form an oxazoline intermediate; second, in a second step, an intramolecular hydrogen transfer takes place to form 5HQ. 5HQ also reacts with hydrochloric acid to produce hydrogen chloride gas and 3-chloroquinoline.
5HQ can be purified through phase chromatography by eluting with chloroform and then collecting fractions that contain it. This purification

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
145.16 g/mol
Formula:
C9H7NO
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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