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(R)-2-Hydroxysuccinic acid methyl ester
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(R)-2-Hydroxysuccinic acid methyl ester

CAS: 83540-94-7

Ref. 3D-FH24501

2gTo inquire
Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
(R)-2-Hydroxysuccinic acid methyl ester
Synonyms:
  • (2R)-Hydroxybutanedioic Acid 1-Methyl Ester
Description:

(R)-2-Hydroxysuccinic acid methyl ester is a potent inhibitor of microglial cells. It has been shown to inhibit the production of inflammatory cytokines such as IL-1β, IL-6, and TNF-α from murine microglial cells. The inhibitory activity was also found in alpha-tocopherol, which is a potent anti-inflammatory agent. Bioactivity guided fractionation led to the isolation of (R)-2-hydroxysuccinic acid methyl ester from the methanolic extract of Staphyleaceae species. This compound was also isolated from Japonica and Megastigmane species and was found to have an inhibitory effect on bv2 microglial cells.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
148.11 g/mol
Formula:
C5H8O5
Purity:
Min. 95%
InChI:
InChI=1S/C5H8O5/c1-10-5(9)3(6)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)/t3-/m1/s1
InChI key:
InChIKey=RTSODCRZYKSCLO-GSVOUGTGSA-N
SMILES:
COC(=O)[C@H](O)CC(=O)O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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