Hydroquinine 1,4-phthalazinediyl diether

CAS: 140924-50-1

Ref. 3D-FH29321

Product Information

• Name: Hydroquinine 1,4-phthalazinediyl diether
• Synonyms: (DHQ)2PHAL, (8alpha,9R,8'''alpha,9'''R)-9,9'-[phthalazine-1,4-diylbis(oxy)]bis(6'-methoxy-10,11-dihydrocinchonan), (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan] [(DHQ)₂PHAL], (DHQ)₂PHAL, (Dhq)2-Phal, (Dhq)2Phal, 1,4-Bis(9-O-dihydroquininyl)phthalazine, 1,4-Bis(9-O-dihydroquinyl)phthalazine, 1,4-Bis(dihydroquinine)phthalazine, Cinchonan, 9,9′′-[1,4-phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxy-, (8α,9R)-(8′′α,9′′R)-
• CAS: 140924-50-1

Description

Hydroquinine 1,4-phthalazinediyl diether is a synthetic compound that has been shown to inhibit leukemia cells. It has been shown to bind to the protein-protein interaction site of the receptor tyrosine kinase and inhibit the activity of this enzyme, thereby inhibiting cellular proliferation. Hydroquinine 1,4-phthalazinediyl diether has also been shown to be an effective drug against leukemia cells in vitro and in vivo. This drug binds reversibly to the active site of protein kinases and inhibits their activation. The hydroxyl group on the quinoline moiety is essential for its binding properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 778.98 g/mol
• Formula: C₄₈H₅₄N₆O₄
• Purity: Min. 95%
• Color/Form: White Powder