4-Hydroxyphenylboronic acid pinacol ester

CAS: 269409-70-3

Ref. 3D-FH33842

Product Information

• Name: 4-Hydroxyphenylboronic acid pinacol ester
• Synonyms: 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, Phenol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

Description

4-Hydroxyphenylboronic acid pinacol ester is a hydrophilic compound that has been used as a long-acting iron chelator. It has been shown to be active in the treatment of anemic patients with chronic kidney disease. 4-Hydroxyphenylboronic acid pinacol ester has been shown to bind to hepcidin, which is a peptide hormone that regulates iron homeostasis in the body by decreasing its absorption from the gut and increasing its excretion. It also binds to functional groups on proteins and other molecules, which allow for selective targeting of certain tissues or cells. This compound can be activated by light, making it photochromic. The addition of an active oxygen atom enables this molecule to react at a faster rate than most compounds and also creates reactive oxygen species (ROS) in humans when activated.

• Brand: Biosynth

Chemical properties

• Molecular weight: 220.1 g/mol
• Formula: C₁₂H₁₇BO₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8,14H,1-4H3
• InChI key: InChIKey=BICZJRAGTCRORZ-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2ccc(O)cc2)OC1(C)C