3-Hydroxy-2-methyl-4-quinolinecarboxylic acid

CAS: 117-57-7

Ref. 3D-FH43999

Product Information

• Name: 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid
• Synonyms: 2-Methyl-3-hydroxy-4-carboxyquinoline, 2-Methyl-3-hydroxyquinoline-4-carboxylic acid, 2-Methyl-3-hydroxyquinoline-4-formic acid, 3-Hydroxy-2-Methylquinoline-4-Carboxylate, 3-Hydroxy-2-Methylquinoline-4-Carboxylic Acid, 3-Hydroxy-2-methylcinchoninic acid, 3-Hydroxy-4-carboxyquinaldine, 3-Hydroxy-4-quinaldinecarboxylic acid, 3-Hydroxyquinaldine-4-Carboxylic, 3-Hydroxyquinaldine-4-Carboxylic Acid, 4-Carboxy-3-hydroxy-2-methylquinoline, 4-Quinolinecarboxylic acid, 3-hydroxy-2-methyl-, Cinchoninic acid, 3-hydroxy-2-methyl-

Description

3-Hydroxy-2-methyl-4-quinolinecarboxylic acid is a quinolone antibiotic that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. 3-Hydroxy-2-methyl-4-quinolinecarboxylic acid has been shown to be an effective antiinfective agent with a broad spectrum of activity against Gram negative and Gram positive bacteria. It has also been shown to have good activity against Mycobacterium tuberculosis, including multidrug resistant strains. The fluorescence properties of 3HQL have been studied using spectroscopy and gravimetric analysis. The quinolone ring system absorbs ultraviolet light in the range of 300 nm to 400 nm and emits blue fluorescence at 470 nm. This molecule reacts with chlorine atoms at low pH levels and releases chloride ions, which may lead to activation energy of less than 10 kcal/mol.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.19 g/mol
• Formula: C₁₁H₉NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C11H9NO3/c1-6-10(13)9(11(14)15)7-4-2-3-5-8(7)12-6/h2-5,13H,1H3,(H,14,15)
• InChI key: InChIKey=RVGATDHHYVSTQG-UHFFFAOYSA-N
• SMILES: Cc1nc2ccccc2c(C(=O)O)c1O