H-Glu-Trp-OH

CAS: 38101-59-6

Ref. 3D-FH44584

Product Information

• Name: H-Glu-Trp-OH
• Synonyms: L-a-Glutamyl-L-tryptophanNSC 334073Oglufanide, 13: PN: JP2010248096 PAGE: 2 claimed protein, 262: PN: EP2161028 PAGE: 12 claimed protein, <span class="text-smallcaps">L</smallcap>-Glutamyl-<smallcap>L</span>-tryptophan, <span class="text-smallcaps">L</smallcap>-Tryptophan, <smallcap>L</span>-α-glutamyl-, <span class="text-smallcaps">L</smallcap>-Tryptophan, N-<smallcap>L</span>-α-glutamyl-, <span class="text-smallcaps">L</smallcap>-α-Glutamyl-<smallcap>L</span>-tryptophan, Ccris 8677, Glu-trp, Glutamyl tryptophan, Glutamyltryptophan, Im 862, Im862, L-Tryptophan, N-L-alpha-glutamyl-, Nsc 334073, Oglufanide, Oglufanide [INN], Thymogen, Timogen, Unii-4Rhy598T5U, alpha-Glutamyltryptophan, α-Glu-Trp
• CAS: 38101-59-6

Description

H-Glu-Trp-OH is a pharmacological agent that has been shown to have anti-angiogenic effects in an isolated heart model. It has been shown to inhibit protein synthesis and growth factor activity, which may lead to the inhibition of angiogenesis. This drug has also been shown to induce pluripotent cells, which can be used for the treatment of autoimmune diseases. H-Glu-Trp-OH is also a monosodium salt that is hydroxylated at C4 position. The compound has been shown to have a high affinity for toll receptor and hydrogen bonds with galleria mellonella, which may be related to its pharmacokinetic properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 333.34 g/mol
• Formula: C₁₆H₁₉N₃O₅
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C16H19N3O5/c17-11(5-6-14(20)21)15(22)19-13(16(23)24)7-9-8-18-12-4-2-1-3-10(9)12/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24)/t11-,13-/m0/s1
• InChI key: InChIKey=LLEUXCDZPQOJMY-AAEUAGOBSA-N
• SMILES: N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O