4-(Hydroxymethyl)phenoxyacetic acid

CAS: 68858-21-9

Ref. 3D-FH46997

Product Information

• Name: 4-(Hydroxymethyl)phenoxyacetic acid
• Synonyms: HMPHMPA Linker, P-(hydroxymethyl)phenoxyacetic acid, Hpa Linker, hmp, Hmpa Linker, Hmp Linker, Fmoc-Scal-Linker (Safety-Catch Linker For Solid Phase Synthesis), [4-(Hydroxymethyl)Phenoxy]Acetate, 4-(Hydroxymethyl)Phenoxy acetic Acid
• CAS: 68858-21-9

Description

4-(Hydroxymethyl)phenoxyacetic acid is a chemical compound that has been found to be an inhibitor of protein synthesis. It has also been shown to inhibit the growth of human leukemia cells, t-cell leukemia cells, and human liver tumor cells. 4-(Hydroxymethyl)phenoxyacetic acid has a ph optimum of 4 and is soluble in water and alcohols. This compound can be synthesized from 4-hydroxymethylbenzoic acid by reacting it with two equivalents of formaldehyde. The reaction is catalyzed by glutaminyl cyclase and acidic pH. 4-(Hydroxymethyl)phenoxyacetic acid is stable to trifluoroacetic acid, but not acidic environments or basic conditions. It has antiviral activity against herpes simplex virus type 1 (HSV-1).

• Brand: Biosynth

Chemical properties

• Molecular weight: 182.17 g/mol
• Formula: C₉H₁₀O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C9H10O4/c10-5-7-1-3-8(4-2-7)13-6-9(11)12/h1-4,10H,5-6H2,(H,11,12)
• InChI key: InChIKey=VUCNQOPCYRJCGQ-UHFFFAOYSA-N
• SMILES: O=C(O)COc1ccc(CO)cc1