8-Hydroxyquinoline-2-carboxylic acid

CAS: 1571-30-8

Ref. 3D-FH57274

Product Information

• Name: 8-Hydroxyquinoline-2-carboxylic acid
• Synonyms: 2-Carboxy-8-hydroxyquinoline, 2-Quinolinecarboxylic acid, 8-hydroxy-, 8-Hydroxy-2-Quinolinecarboxylic Acid, 8-Hydroxy-Quinaldicaci, 8-Hydroxyquinaldic Acid, 8-Hydroxyquinaldinic acid, 8-Hydroxyquinoline-2-Carboxylate, 8-Hydroxyquinoline-2-Carboxylic Acid 98%, Methyl 8-Hydroxyquinoline-2-Carboxylate, Quinaldic acid, 8-hydroxy-, Rarechem Al Bo 1187

Description

8-Hydroxyquinoline-2-carboxylic acid is a 3-hydroxyanthranilic acid derivative that is often used as a biomarker of urine. The 8OHQA can be synthesized from 3-hydroxyanthranilic acid by the action of xanthine oxidase and hydrogen peroxide, and it has been shown to be an inhibitor of protein synthesis. This inhibition may be due to its ability to form hydrogen bonds with the hydroxyl group on the ribose side chain and its ability to coordinate with metals. 8OHQA has been shown to have anti-inflammatory effects in bladder cancer cells, which may be due to its ability to inhibit prostaglandin synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 189.17 g/mol
• Formula: C₁₀H₇NO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)
• InChI key: InChIKey=UHBIKXOBLZWFKM-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc2cccc(O)c2n1