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4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile
CAS: 189956-45-4
Ref. 3D-FH72076
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile
Synonyms:
- 4-N[2(4-hydroxypyrimidinyl)]aminobenzonnitrile
- 4-[(1,4-Dihydro-4-Oxo-2-Pyrimidinyl)Amino]Benzonitrile
- 4-[(4-Hydroxy-pyrimidin-2-yl)amino]-benzonitrile
- 4-[(6-Oxo-1,6-Dihydropyrimidin-2-Yl)Amino]Benzonitrile
- Benzonitrile, 4-[(1,4-dihydro-4-oxo-2-pyrimidinyl)amino]-
Description:
Rilpivirine is an antiviral drug that is used in the treatment of HIV. It inhibits the viral enzyme reverse transcriptase, which is needed for the production of viral DNA from RNA. Rilpivirine is a prodrug that undergoes hydrolysis by esterases to form its active metabolite, 4-[(4-hydroxy-2-pyrimidinyl)amino]benzonitrile (4HPBA). 4HPBA binds to reverse transcriptase and prevents DNA synthesis. Rilpivirine has been shown to be active against HIV strains resistant to other anti-HIV drugs such as zidovudine, abacavir and lamivudine.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
212.21 g/mol
Formula:
C11H8N4O
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:
