2'-Hydroxyacetophenone-5'-carboxylic acid

CAS: 16357-40-7

Ref. 3D-FH76237

Product Information

• Name: 2'-Hydroxyacetophenone-5'-carboxylic acid

Description

2'-Hydroxyacetophenone-5'-carboxylic acid is an acidic compound that has been shown to be cytotoxic in vivo and in vitro. The compound is a chalcone, which are compounds that are synthesized from the condensation of acetyl-CoA with three molecules of malonyl-CoA. 2'-Hydroxyacetophenone-5'-carboxylic acid has been shown to induce apoptosis by binding to DNA and RNA and inhibiting protein synthesis. This compound also inhibits the growth of human cancer cells (e.g., MRC-5 cells) through competitive inhibition of the enzyme protein kinase C θ (PKCθ).

• Brand: Biosynth

Chemical properties

• Molecular weight: 180.16 g/mol
• Formula: C₉H₈O₄
• Purity: Min. 95%
• InChI: InChI=1S/C9H8O4/c1-5(10)7-4-6(9(12)13)2-3-8(7)11/h2-4,11H,1H3,(H,12,13)
• InChI key: InChIKey=FPBXWXGOFQSROI-UHFFFAOYSA-N
• SMILES: CC(=O)c1cc(C(=O)O)ccc1O