4-Imidazoleacetic acid HCl

CAS: 3251-69-2

Ref. 3D-FI00326

Product Information

• Name: 4-Imidazoleacetic acid HCl
• Synonyms: (1H-Imidazol-4-yl)acetic acid hydrochloride, (1H-Imidazol-5-yl)acetic acid hydrochloride, 1H-Imidazole-4-acetic acid, hydrochloride, 1H-Imidazole-4-acetic acid, monohydrochloride, 1H-Imidazole-5-acetic acid hydrochloride, 1H-Imidazole-5-acetic acid, hydrochloride (1:1), 1H-imidazol-5-ylacetate, 1H-imidazol-5-ylacetic acid, 1H-imidazol-5-ylacetic acid hydrochloride (1:1), 2-(1H-Imidazol-4-yl)acetic acid hydrochloride, 2-(1H-Imidazol-5-yl)acetic acid hydrochloride, Imidazol-4-acetic acid hydrochloride, Imidazole-4-acetic acid hydrochloride, Imidazole-4-acetic acid monohydrochloride, Imidazoleacetic acid hydrochloride
• CAS: 3251-69-2

Description

4-Imidazoleacetic acid HCl is a fluorescent probe that binds to the α1 subunit of the dinucleotide phosphate (NADH) oxidoreductase. It has been shown to inhibit mitochondrial functions, which may be due to its ability to inhibit the pentose phosphate pathway and reduce reactive oxygen species levels. 4-Imidazoleacetic acid HCl has also shown inhibitory properties against congestive heart failure by acting on the mitochondria and inhibiting energy metabolism. It can also be used as a chemical biology tool for studying protein interactions with NADH dehydrogenase. The x-ray crystal structures have revealed that 4-imidazoleacetic acid HCl binds to the active site of NADH oxidoreductase with an orientation that mimics a substrate molecule. This allows it to bind tightly and disrupt enzyme activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 162.57 g/mol
• Formula: C₅H₆N₂O₂·HCl
• Purity: Min. 95%
• Color/Form: Powder