Product Information
- 1-Amino-4-iodobenzene
- 1-Iodo-4-aminobenzene
- 4-Aminoiodobenzene
- 4-Iodanilin
- 4-Iodoanilina
- 4-Iodoaniline
- 4-Iodobenzenamine
- 4-Iodobenzeneamine
- 4-Iodophenylamine
- Aniline, 4-Iodo-
- See more synonyms
- Aniline, p-iodo-
- Nsc 9246
- p-Aminoiodobenzene
- p-Aminophenyl iodide
- p-Iodoaniline
4-Iodoaniline is a chemical compound with the molecular formula C6H5I. It is an organic aromatic compound that can be synthesized by adding iodine to aniline in the presence of hydrochloric acid and sodium hydroxide. 4-Iodoaniline is soluble in water, alcohols, and ethers, but insoluble in benzene or acetone. The redox potential of 4-iodoaniline lies between +0.1 V and +0.3 V, which makes it suitable as a model system for studying enzyme activities such as the Suzuki coupling reaction.
The reaction solution containing 4-iodoaniline may be used as an anticancer agent against leukemia cells. This agent inhibits DNA synthesis by binding to the enzyme dihydrofolate reductase (DHFR) and inhibiting its activity. Hydrochloric acid is added to the process to remove water from the reaction solution and produce a dry product with high
