2-Iminobiotin

CAS: 13395-35-2

Ref. 3D-FI09932

Product Information

• Name: 2-Iminobiotin
• Synonyms: Guanidinobiotin
• CAS: 13395-35-2

Description

2-Iminobiotin is a reactive molecule that has been used as an experimental model for the study of protein synthesis, energy metabolism, and neuroprotection. The binding of 2-Iminobiotin to streptavidin has been shown to inhibit GABA-induced currents in rat brain cells. This compound also has a neuroprotective effect on neurons by inhibiting glutamate-induced excitotoxicity. 2-Iminobiotin has also been found to have a high affinity for human serum albumin, which may be due to its hydrogen bond formation with the NH group of Serine residues on the protein.
2-Iminobiotin binds to specific receptors in the central nervous system and blocks the binding of gamma-aminobutyric acid (GABA) or glutamate to their receptors. This results in increased levels of GABA and decreased levels of glutamate, leading to neuroprotection.
2-Iminobiotin can be detected by HPLC with

• Brand: Biosynth

Chemical properties

• Molecular weight: 243.33 g/mol
• Formula: C₁₀H₁₇N₃O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C10H17N3O2S/c11-10-12-6-5-16-7(9(6)13-10)3-1-2-4-8(14)15/h6-7,9H,1-5H2,(H,14,15)(H3,11,12,13)/t6-,7-,9-/m0/s1
• InChI key: InChIKey=WWVANQJRLPIHNS-ZKWXMUAHSA-N
• SMILES: NC1=N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]2N1