Z-Ile-Pro-OH

CAS: 13211-37-5

Ref. 3D-FI111543

Product Information

• Name: Z-Ile-Pro-OH
• Synonyms: <span class="text-smallcaps">L</smallcap>-Proline, 1-[N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-isoleucyl]-, <span class="text-smallcaps">L</smallcap>-Proline, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-isoleucyl-, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</smallcap>-isoleucyl-<smallcap>L</span>-proline, N-[(benzyloxy)carbonyl]isoleucylproline, NSC 333754, Proline, 1-(N-carboxy-<span class="text-smallcaps">L</smallcap>-isoleucyl)-, N-benzyl ester, <smallcap>L</span>-, Proline, 1-(N-carboxy-<span class="text-smallcaps">L</span>-isoleucyl)-, N-benzyl ester

Description

Z-Ile-Pro-OH is an experimental inhibitor of protein synthesis that has been shown to inhibit collagenase and pancreatic proteases. Z-Ile-Pro-OH inhibits the second order rate constant of hydrolysis by a kinetic method. The pH optimum of Z-Ile-Pro-OH is 7.5 and it does not hydrolyze at this pH. Z-Ile-Pro-OH binds to the active site of the protease, inhibiting its activity and has been shown to be non toxic in mice. The synthetic inhibitor has been used as a nutritional supplement for humans because it does not affect the pancreas or liver when ingested orally, but has no effect on bone growth.

• Brand: Biosynth

Chemical properties

• Molecular weight: 362.42 g/mol
• Formula: C₁₉H₂₆N₂O₅
• Purity: Min. 95%