Indole-3-glyoxylyl chloride

CAS: 22980-09-2

Ref. 3D-FI12043

Product Information

• Name: Indole-3-glyoxylyl chloride
• Synonyms: (1H-Indol-3-yl)oxoacetyl chloride, 1H-Indole-3-acetyl chloride, α-oxo-, 1H-indol-3-yl(oxo)acetyl chloride, 2-(1H-Indol-3-yl)-2-oxoacetyl chloride, 2-(3-Indolyl)-2-oxoacetyl chloride, 3-Indoleglyoxylyl chloride, 3-Indolylglyoxylyl chloride, ALPHA-Oxo-1H-indole-3-acetyl chloride, Indole-3-glyoxyloyl chloride, NSC 128332, alpha-Oxoindoleacetyl chloride, α-Oxo-1H-indole-3-acetyl chloride

Description

Pityriacitrin is a natural compound that is structurally related to indole-3-glyoxylyl chloride. The primary effect of pityriacitrin is to inhibit the binding of ligands to benzodiazepine receptors, which are the 5-HT2 type. It also inhibits glycogen synthase kinase 3 (GSK3), a protein kinase that regulates glycogen synthesis and glucose metabolism. Pityriacitrin has been shown to have anticancer effects through inhibition of polymerase chain reaction (PCR) in human cancer cells, and has been shown to produce an increase in locomotor activity in mice.

• Brand: Biosynth

Chemical properties

• Molecular weight: 207.61 g/mol
• Formula: C₁₀H₆ClNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H6ClNO2/c11-10(14)9(13)7-5-12-8-4-2-1-3-6(7)8/h1-5,12H
• InChI key: InChIKey=FPEGGKCNMYDNMW-UHFFFAOYSA-N
• SMILES: O=C(Cl)C(=O)c1c[nH]c2ccccc12