2-(4-Isopropylphenyl)quinoline-4-carbonyl chloride

CAS: 1160264-73-2

Ref. 3D-FI120650

Product Information

• Name: 2-(4-Isopropylphenyl)quinoline-4-carbonyl chloride
• Synonyms: 4-quinolinecarbonyl chloride, 2-[4-(1-methylethyl)phenyl]-

Description

2-(4-Isopropylphenyl)quinoline-4-carbonyl chloride is a potent inducers of human lymphocytes. It has been shown to be clastogenic and mutagenic, inducing DNA lesions in vitro. This compound induces the production of reactive oxygen species and results in the formation of naphthofurans, which are reactive intermediates that can form DNA adducts or cause mutations. 2-(4-Isopropylphenyl)quinoline-4-carbonyl chloride does not show carcinogenic activity in vivo, but has been shown to cause cancer in animal studies. This compound also causes alkylation of DNA bases, which may lead to cancer as well.

• Brand: Biosynth

Chemical properties

• Molecular weight: 309.79 g/mol
• Formula: C₁₉H₁₆ClNO
• Purity: Min. 95%
• InChI: InChI=1S/C19H16ClNO/c1-12(2)13-7-9-14(10-8-13)18-11-16(19(20)22)15-5-3-4-6-17(15)21-18/h3-12H,1-2H3
• InChI key: InChIKey=ATVGEUWNIIPGSJ-UHFFFAOYSA-N
• SMILES: CC(C)c1ccc(-c2cc(C(=O)Cl)c3ccccc3n2)cc1