1H-Imidazo[4,5-b]pyridin-2(3H)-one
CAS: 16328-62-4
Ref. 3D-FI139719
1g | To inquire | |
2g | To inquire | |
5g | To inquire | |
250mg | To inquire | |
500mg | To inquire |
Product Information
- 2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-
- 1H-Imidazo[4,5-B]Pyridin-2(3H)-One
1H-Imidazo[4,5-b]pyridin-2(3H)-one is a nitro derivative of an adenosine receptor antagonist. It displays high affinity and selectivity for the A3 adenosine receptor. 1H-Imidazo[4,5-b]pyridin-2(3H)-one inhibits the activity of protein kinases by binding to the ATP binding site on the enzyme. This drug has been shown to inhibit phosphorylation of cAMP response element binding protein (CREB) in human lung cells, which may be due to its inhibition of CREB kinase activity. The pharmacokinetic profile of 1H-imidazo[4,5-b]pyridin-2(3H)-one is not well understood, but it is thought that it is eliminated primarily by renal excretion.
1H-Imidazo[4,5-b]pyr
Chemical properties
Technical inquiry about: 3D-FI139719 1H-Imidazo[4,5-b]pyridin-2(3H)-one
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