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3-Iodoquinolin-4-ol
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3-Iodoquinolin-4-ol

CAS: 64965-48-6

Ref. 3D-FI139955

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Estimated delivery in United States, on Tuesday 7 Jan 2025

Product Information

Name:
3-Iodoquinolin-4-ol
Synonyms:
  • 3-Iodo-4-quinolinol
  • 4-Quinolinol, 3-iodo-
Description:

3-Iodoquinolin-4-ol is a synthetic compound that inhibits bacterial growth by inhibiting the synthesis of RNA and DNA. It has been shown to be active against Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis, but not against Gram-negative bacteria such as Escherichia coli. 3-Iodoquinolin-4-ol also has potentiating effects on the CFTR protein in cells with the F508del mutation. This mutation affects the chloride channel present in the cell membrane, which leads to an increased amount of salt in body fluids and can cause cystic fibrosis (CF). The terminal alkynes within this molecule are bioisosteres for amides when they are coupled to boronic acids, which were used in an assay to measure bacterial activity.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
271.05 g/mol
Formula:
C9H6INO
Purity:
Min. 95%
MDL:
Melting point:
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Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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