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5-Iodo-7H-pyrrolo[2,3-d]pyrimidine
CAS: 175791-53-4
Ref. 3D-FI154981
| 1g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
5-Iodo-7H-pyrrolo[2,3-d]pyrimidine is a palladium-catalyzed cross-coupling reaction that can be used to synthesize 5-(iodomethyl)benzofuran. The palladium catalyst is generated in situ from the reaction of palladium chloride and triethylamine. The reaction uses a Suzuki coupling with 2 molar equivalents of 7H-pyrrolo[2,3-d]pyrimidine and 1 equivalent of phenylboronic acid. It proceeds via an oxidative addition followed by reductive elimination. The product is purified by column chromatography using silica gel as the stationary phase.
Chemical properties
Technical inquiry about: 3D-FI154981 5-Iodo-7H-pyrrolo[2,3-d]pyrimidine
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