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Indomethacin methyl ester
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Indomethacin methyl ester

CAS: 1601-18-9

Ref. 3D-FI24586

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Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
Indomethacin methyl ester
Synonyms:
  • 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid methyl esterMethyl N-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolyla cetateL 588983
  • 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid methyl ester
  • 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, methyl ester
  • Brn 0496619
  • Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-, methyl ester
  • Indometacin methylester
  • L 588983
  • Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate
  • Methyl 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
  • Methyl N-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetate
  • See more synonyms
  • [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
  • methyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate
  • 5-22-05-00240 (Beilstein Handbook Reference)
  • Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
  • Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
Description:

Indomethacin methyl ester is a nonsteroidal anti-inflammatory drug. It inhibits the biosynthesis of prostaglandins, which are hormones that cause inflammation and pain. Indomethacin methyl ester has been shown to be effective in treating inflammatory diseases such as asthma, arthritis, and bursitis. The drug is an amide with two functional groups: an ethyl ester and a hydroxyl group. The medication is metabolized into indomethacin by hydrolysis of the ester bond and demethylation of the hydroxyl group. The drug binds to particle surfaces by hydrogen bonding interactions and does not penetrate cell membranes well. This may explain why it has a lower effective dose than other NSAIDs such as ibuprofen or naproxen sodium. Indomethacin methyl ester can also be administered orally or intravenously at high doses for severe cases of inflammation or pain.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
371.81 g/mol
Formula:
C20H18ClNO4
Purity:
Min. 95%
InChI:
InChI=1S/C20H18ClNO4/c1-12-16(11-19(23)26-3)17-10-15(25-2)8-9-18(17)22(12)20(24)13-4-6-14(21)7-5-13/h4-10H,11H2,1-3H3
InChI key:
InChIKey=OKHORWCUMZIORR-UHFFFAOYSA-N
SMILES:
COC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12
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Hazard Info

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