Indole-3-propanol

CAS: 3569-21-9

Ref. 3D-FI30475

Product Information

• Name: Indole-3-propanol
• Synonyms: 3-(3-Indolyl)propanol, 1H-Indole-3-propanol, 3-(1H-Indol-3-yl)-1-propanol, 3-(1H-Indol-3-yl)propanol, 3-(1H-indol-3-yl)propan-1-ol, 3-(3-Hydroxypropyl)-1H-indole, 3-(3-Hydroxypropyl)indole, 3-(3-Indolyl)-1-propanol, Homotryptophol
• CAS: 3569-21-9

Description

Indole-3-propanol is a reversible inhibitor of the enzyme dihydrofolate reductase that blocks the synthesis of purine nucleotides. It has been shown to have a regulatory effect on bacterial growth and may be used as an antimicrobial agent. Indole-3-propanol is an inhibitor of the enzyme dihydrofolate reductase, which catalyzes the reduction of dihydrofolic acid to tetrahydrofolic acid. This conversion is essential for DNA synthesis and repair in bacteria. Indole-3-propanol inhibits this reaction reversibly by binding to the hydroxy group in the active site of the enzyme, thereby blocking access to substrate analogues such as phosphoribosyl pyrophosphate (PRPP). The compound also inhibits human serum proteins, such as albumin, which are involved in metabolizing drugs. Molecular modeling studies suggest that indole-3-propanol binds to two l

• Brand: Biosynth

Chemical properties

• Molecular weight: 175.23 g/mol
• Formula: C₁₁H₁₃NO
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C11H13NO/c13-7-3-4-9-8-12-11-6-2-1-5-10(9)11/h1-2,5-6,8,12-13H,3-4,7H2
• InChI key: InChIKey=LYPSVQXMCZIRGP-UHFFFAOYSA-N
• SMILES: OCCCc1c[nH]c2ccccc12