Imidazo[1,2-a]pyridin-3-yl-acetic acid

CAS: 17745-04-9

Ref. 3D-FI32031

Product Information

• Name: Imidazo[1,2-a]pyridin-3-yl-acetic acid
• Synonyms: (3-Imidazo(1,2-A)pyridine)acetic acid, 2-(Imidazo[1,2-A]Pyridin-3-Yl)Acetic Acid, 2-(Imidazolo[1,2-a]pyridin-3-yl)acetic acid, Imidazo(1,2-a)pyridine-3-acetiacide, Imidazo(1,2-a)pyridine-3-aceticacid, Imidazo[1,2-a]pyridin-3-ylacetic acid, Imidazo[1,2-a]pyridine-3-acetic acid, Minodronic acid Intermediate B

Description

Imidazo[1,2-a]pyridin-3-yl-acetic acid is a drug that belongs to the class of HIV protease inhibitors. It is a potent inhibitor of the human proprotein convertase subtilisin/kexin type 9 (PCSK9) enzyme. Imidazo[1,2-a]pyridin-3-yl-acetic acid has been shown to inhibit PCSK9 activity in postprandial plasma and hepatic lipase in vitro. PCSK9 inhibition leads to an increase in high density lipoprotein cholesterol (HDL) levels, which may be beneficial for patients with atherosclerotic cardiovascular disease. Imidazo[1,2-a]pyridin-3-yl-acetic acid also has antiatherogenic properties through its ability to lower triglycerides and free fatty acids. The reaction solution used for this experiment was hydrochloric acid (HCl

• Brand: Biosynth

Chemical properties

• Molecular weight: 176.17 g/mol
• Formula: C₉H₈N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C9H8N2O2/c12-9(13)5-7-6-10-8-3-1-2-4-11(7)8/h1-4,6H,5H2,(H,12,13)
• InChI key: InChIKey=ZVBVKRNOISRONE-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1cnc2ccccn12