(+)-2,2'-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline]

CAS: 150529-93-4

Ref. 3D-FI45919

Product Information

• Name: (+)-2,2'-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline]
• Synonyms: (R)-(+)-2,2'-Isopropylidenebis(4-Phenyl-2-Oxazoline), (R,R)-2,2-Bis(4-Phenyl-2-Oxazolin-2-Yl)Propane, (R,R)-2,2'-Isopropylidenebis(4-Phenyl-2-Oxazoline), (+)-2,2'-Isopropylidenebis[(4R)-4-Phenyl-2-Oxazoline], (R,R)-2,2μ-Isopropylidenebis(4-phenyl-2-oxazoline), (R,R)-2,2μ-Bis(4-phenyl-2-oxazolin-2-yl)propane, (4R,4'R)-2,2'-propane-2,2-diylbis(4-phenyl-4,5-dihydro-1,3-oxazole)

Description

(+)-2,2'-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] is a chiral molecule that can be used as a ligand in asymmetric synthesis. It has been shown to undergo desymmetrization in the presence of copper and ammonia ions. This reaction produces (+)-2,2'-isopropylidenebis[(4S)-4-phenyl-2-oxazoline], which can be used in other reactions to produce a variety of chiral building blocks. The use of this ligand has also been shown to lead to the formation of tropones from alcohols and aminoaldehydes in an organic solvent at room temperature under kinetic conditions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 334.41 g/mol
• Formula: C₂₁H₂₂N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C21H22N2O2/c1-21(2,19-22-17(13-24-19)15-9-5-3-6-10-15)20-23-18(14-25-20)16-11-7-4-8-12-16/h3-12,17-18H,13-14H2,1-2H3/t17-,18-/m0/s1
• InChI key: InChIKey=JTNVCJCSECAMLD-ROUUACIJSA-N
• SMILES: CC(C)(C1=N[C@H](c2ccccc2)CO1)C1=N[C@H](c2ccccc2)CO1