L-Isoleucine benzyl ester 4-toluenesulfonate salt

CAS: 16652-75-8

Ref. 3D-FI47554

Product Information

• Name: L-Isoleucine benzyl ester 4-toluenesulfonate salt
• Synonyms: L-Ile-OBzl·TosOH, (2S,3S)-1-(benzyloxy)-3-methyl-1-oxopentan-2-aminium 4-methylbenzenesulfonate, <span class="text-smallcaps">L</span>-Isoleucine benzyl ester p-toluenesulfonate, <span class="text-smallcaps">L</span>-Isoleucine benzyl ester tosylate, <span class="text-smallcaps">L</span>-Isoleucine, phenylmethyl ester, 4-methylbenzenesulfonate, <span class="text-smallcaps">L</span>-Isoleucine, phenylmethyl ester, 4-methylbenzenesulfonate (1:1), Benzyl <span class="text-smallcaps">L</span>-isoleucinate p-toluenesulfonate, Benzyl <span class="text-smallcaps">L</span>-isoleucinate tosylate, H-Ile-OBzl.Tos, H-Ile-OBzl・Tosh, Isoleucine benzyl ester p-toluenesulfonate, Isoleucine benzyl ester tosylate, Isoleucine, benzyl ester, p-toluenesulfonate, <span class="text-smallcaps">L</span>-, L-Ile-OBzl TsOH, L-Isoleucine Benzyl Ester 4-Toluenesulphonate, L-isoleucine benzyl ester 4-toluenesulfonate salt, L-Isoleucine, phenylmethyl ester, 4-methylbenzenesulfonate (1:1), Isoleucine, benzyl ester, p-toluenesulfonate, L-, L-Isoleucine, phenylmethyl ester, 4-methylbenzenesulfonate, L-Isoleucine benzyl ester p-toluenesulfonate

Description

L-Isoleucine benzyl ester 4-toluenesulfonate salt is a prodrug of l-isoleucine. It has been shown to increase the intestinal absorption of valacyclovir, a drug that is used to treat herpes simplex virus infections, by increasing its transport. L-Isoleucine benzyl ester 4-toluenesulfonate salt is converted to l-isoleucine in the intestine and binds to amino acid transporter proteins, which are responsible for transporting amino acids into cells. The affinity of this prodrug for these transporters is greater than that of l-amino acid homogenates, which increases its uptake. This prodrug is also activated by metoprolol and enhances the uptake of this β blocker.

• Brand: Biosynth

Chemical properties

• Molecular weight: 393.5 g/mol
• Formula: C₁₃H₁₉NO₂·C₇H₈O₃S
• Purity: Min. 95%