Product Information
- 1H-Indole-5-carboximidamide
1H-Indole-5-carboxamidine is a compound with a hydroxyl group. It has been shown to inhibit the activity of serine protease and coagulation factors, which are important for coagulation. 1H-Indole-5-carboxamidine also inhibits the activity of urokinase-type plasminogen activator, an enzyme that breaks down blood clots. This drug has been shown to inhibit the formation of blood clots in both animal and human studies. The molecular modeling study revealed that 1H-indole-5-carboxamidine binds to benzamidine, a substrate of serine proteases, through hydrogen bonding interactions and chlorine atom. This binding prevents the substrate from interacting with urokinase type plasminogen activator (uPA) and prevents it from cleaving prothrombin to form thrombin, leading to inhibition of coagulation.
Chemical properties
Technical inquiry about: 3D-FI51161 1H-Indole-5-carboxamidine
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
