Imidazo[1,2-A]Pyridine-2-Carboxylic Acid

CAS: 64951-08-2

Ref. 3D-FI56326

Product Information

• Name: Imidazo[1,2-A]Pyridine-2-Carboxylic Acid
• Synonyms: Imidazo[1,2-a]pyridine-2-carboxylic acid, Imidazo[1,2-A]Pyridine-2-Carboxylate

Description

Imidazo[1,2-A]Pyridine-2-Carboxylic Acid is an amide that has been isolated from the marine sponge Spongia officinalis. It has shown inhibitory effects against Cox-1 and Cox-2 enzymes and is a traceless inhibitor of platelet aggregation. Imidazo[1,2-A]Pyridine-2-Carboxylic Acid inhibits COX enzymes by reacting with the heme moiety of the enzyme in a chemical reaction to form a covalent adduct. This compound also inhibits candida glabrata, gastroduodenal ulcers, and gastric lesions. Imidazo[1,2-A]Pyridine-2-Carboxylic Acid has been found to be an inhibitor of acetylcholinesterase (AChE) activity in vitro at concentrations greater than 1 mM. It binds to the active site of ACh

• Brand: Biosynth

Chemical properties

• Molecular weight: 162.15 g/mol
• Formula: C₈H₆N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H6N2O2/c11-8(12)6-5-10-4-2-1-3-7(10)9-6/h1-5H,(H,11,12)
• InChI key: InChIKey=WQLJLPDGSLZYEP-UHFFFAOYSA-N
• SMILES: O=C(O)c1cn2ccccc2n1