4-Iodo-2-methylanisole
CAS: 75581-11-2
Ref. 3D-FI64636
| 10g | 53.00 € | ||
| 25g | 116.00 € | ||
| 50g | 189.00 € | ||
| 100g | 325.00 € | ||
| 250g | 645.00 € |
Product Information
- 1-Iodo-4-methoxy-3-methylbenzene
- 4-Iodo-2-methyl-1-methoxybenzene
- 4-Methoxy-3-methyliodobenzene
- 5-Iodo-2-methoxytoluene
- Benzene, 4-iodo-1-methoxy-2-methyl-
4-Iodo-2-methylanisole (4IM) is a naphthalene that is regiospecifically eliminated after activation by nitrate in an acidic medium. The hydrochloride salt of 4IM, koenigicine, has been shown to produce estrogen levels in the female rat similar to those produced by 17β-estradiol. The synthesis of 4IM involves the nitration of 2-methylanisole followed by iodine oxidation. This reaction produces a mixture of mono-, di-, and tri-iodonapthalenes. The product obtained from this reaction is purified with column chromatography or recrystallization.
Theory predicts that 4IM will be oxidized to 4-iodo-2,6-dimethylanisole by terpene oxidants such as acetonitrile or ozone.
Chemical properties
Technical inquiry about: 3D-FI64636 4-Iodo-2-methylanisole
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