Product Information
5-Iodo-2-methoxybenzyl alcohol (5IMB) is a conjugate that inhibits tubulin polymerization and mitochondrial membrane integrity. It has significant inhibitory effects on colchicine-induced apoptosis in colon cancer cells, inducing apoptotic cell death by the activation of caspase 3 and annexin. 5IMB also has an inhibitory effect on mitochondria, leading to mitochondrial membrane depolarization and apoptotic cell death. This conjugate also induces the death of human cancer cells, specifically mcf-7, which are involved in tumour growth and metastasis. The mechanism of action for 5IMB is through its ability to induce mitochondrial membrane depolarization, leading to apoptotic cell death.
Chemical properties
Technical inquiry about: 3D-FI67388 5-Iodo-2-methoxybenzyl alcohol
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